Puljic et al, The risk of infant and fetal death by each additional week of expectant management in intrahepatic cholestasis of pregnancy by gestational age. Am J Obstet Gynaecol, 2015 May, 212 (5):667b

Lo et al, Intrahepatic cholestasis of pregnancy and timing of delivery. The journal of Maternal-Fetal & Neonatal Medicine, 28:18, 2254-2258 2015

Available from the RCM Library

Association of adverse perinatal outcomes of intrahepatic cholestasis of pregnancy with biochemical markers: results of aggregate and individual patient data meta-analyses - Lancet  Volume 393, ISSUE 10174, P899-909, March 02, 2019

NIHR article Friday February 5 2019: Blood test could tell risk of stillbirth

Miragoli et al, A Protective Antiarrhythmic Role of Ursodeoxycholic Acid in an InVitro Rat Model of the Cholestatic

Fetal Heart Hepatology, Vol. 54, No. 4, 2011

Williamson et al, Bile acid signalling in fetal tissues: implications for intrahepatic cholestasis of pregnancy Digestive Diseases, Vol 29, No 1 , June 2011

Geenes et al, A placental phenotype of intrahepatic cholestasis of pregnancy. Placenta 2011 Dec;32(12) 1026-32

Available from the RCM Library

Chappell LC, Chambers J, Dixon PH, Dorling J, Hunter R, Bell JL, Bowler U, Hardy P, Juszczak E, Linsell L, Rounding C, Smith C, Williamson C, Thornton JG. Ursodeoxycholic acid versus placebo in the treatment of women with intrahepatic cholestasis of pregnancy (ICP) to improve perinatal outcomes: protocol for a randomised controlled trial (PITCHES). Trials 2018; 19: 657.

Dixon et al, Heterozygous MDR3 missense mutation associated with intrahepatic cholestasis of pregnancy: evidence for a defect in protein trafficking Hum. Mol. Gent. (2000) 9 (8) 1209-1217

Dixon et al, A comprehensive analysis of common genetic variation around six candidate loci for intrahepatic cholestasis of pregnancy AM J Gastroenterology 2014 Jan; 109(1):76-84

Hep C - Marschall HU, Shemer EW, Ludvigsson JF, Stephansson O. Intrahepatic cholestasis of pregnancy and associated hepatobiliary disease: a population-based cohort study. Hepatology 2013; 58:1385–91

Locatelli et al, Hepatitis C virus infection is associated with a higher incidence of cholestasis of pregnancy, British Journal of Obstetrics and Gynaecology May 1999, Vol 106, pp. 498-500

Beuers et al, Changing Nomenclature for PBC: ‘Cirrhosis to Cholangitis’ Clinics and Research in Hepatology and Gastroenterology (2015) 39, e57-e59

Available from the RCM Library

Abu-Hayyeh et al, Prognostic and mechanistic potential of progesterone sulfates in intrahepatic cholestasis of pregnancy and pruritus gravidarum Hepatology 2015 doi:10.1002/hep.28265 (epub ahead of print)

Song et al, 2014 Transcriptional dynamics of bile salt export pump during pregnancy: mechanisms and implications in intrahepatic cholestasis of pregnancy. Hepatology 2014 dec 60(6): p1993-2007

ICP Support provides a support and information line for women and anyone affected by ICP who want to know more about it. 

ICP Support information leaflet (2019)

Andreas E. Kremer et al. (2010) Lysophosphatidic acid is a potential mediator of cholestatic pruritus. Gastroenterology, Volume 139, Pages 1008–1018

Kremer et al, 2015 Autotaxin activity has a higher accuracy to diagnose intrahepatic cholestasis of pregnancy Journal of Hepatology, 2015, vol 62:897-904

Abu-Hayyeh et al, 2015, Prognostic and Mechanistic Potential of Progesterone Sulfates in Intrahepatic Cholestasis of Pregnancy and Pruritus Gravidarum, Hepatology

EASL Clinical practice Guidelines: Management of cholestatic liver diseases Journal of Hepatology 51 (2009) 237-267

Obstetric Cholestasis (Green-top Guideline No. 43) RCOG

Marschall, HU., Management of intrahepatic cholestasis of pregnancy, Expert Rev. Gastroenterol. Hepatolol. 9(10), 1273-1279 2015

Available from the RCM Library